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GHB is a powerful synthetic drug that has euphoric and sedative effects. It acts as depressant on the central nervous system. It is rapidly metabolized by the body. The effects of the drug can be felt within fifteen to twenty minutes after ingestion. GHB can cause dizziness, nausea, vomiting, confusion, seizures, respiratory depression, and intense […]

GHB is available as an odorless, colorless drug that may be combined with alcohol and given to unsuspecting victims prior to sexual assaults. It may have a soapy or salty taste. Use for sexual assault has resulted in GHB being known as a date rape drug. Victims become incapacitated due to the sedative effects of […]

γ-Hydroxybutyric acid (GHB), also known as 4-hydroxybutanoic acid, is a naturally occurring neurotransmitter and a psychoactive drug. Chemically closely related to GABA, it acts on the GABA receptor and on the GHB receptor. GHB has been used in a medical setting as a general anesthetic, for cataplexy, narcolepsy, and alcoholism. It is also used illegally […]

For the thirty years prior to 1990, the scientific papers on GHB were unanimous in reporting numerous beneficial physiological effects and the absence of long-term negative effects. In 1964, Laborit listed “very low toxicity” as one of the “principle elements” of the compound’s pharmacology. In a 1969 report on GHB’s anesthetic uses, Vickers referred to […]

GHB, or gamma-hydroxybutyrate, is a normal component of mammalian metabolism. It is found naturally in every cell in the human body and is most properly considered a nutrient. In the brain, the highest amounts are found in the hypothalamus and basal ganglia [Gallimberti, 1989]. GHB is found in greater concentrations in kidney, heart, skeletal muscles, […]